RESEARCH
REDEFINED

The biggest hurdles that exosomes face in the quest to be FDA-approved as a therapeutic are their heterogeneity and the lack of standardization. In other words, their different sizes and the different protocols that labs use to acquire and load the exosomes creates too much variability to be classified as a standard biologic that can be used in patients. Let’s break it down further… First, there is a size problem . One exosome, or ‘package’ might be large and fully loaded. An

If you ever need to determine if you are in the driving seat of your mind, try taking a journey on the subway trains. It sounds so simple, but it is a deceptive beast that truly challenges you and will quickly reveal to you who is in command. Imagine you are tired from a long day at work, but the train is delayed. You would probably feel broken down, frustrated and upset. Knees would bounce vigorously as anxiety increases. Patience and peace have left the moment it was announ

What happens when communication breaks down? We saw from Part 1 that the delivery mechanism is indeed a delicate process that is heavily reliant on the targeting abilities of exosomes and good communication. But similar to FedEx package deliveries, poor communication or specificity can lead to detrimental results. No matter how good the system is, we may have experienced at least one bad delivery. And that could be due to inclement weather, poor traffic and road conditions or